In his sermon "What Is Man?," John Wesley spoke of the human being as a "curious machine," reflecting the eighteenth-century view of the person as a set of complex mechanisms animated by the soul. The rapid rate of technological development in recent decades is opening toward a future in which the centrality and uniqueness of human beings is undergoing a shift. Developments in robotics, artificial intelligence, surveillance, autonomous weapons, human enhancement, and genetic modification raise an array of questions for the Christian tradition. The awareness of the negative impact of human activity on the natural environment is challenging the traditional view of humanity as having a uniquely privileged role at the heart of creation. This collection of essays addresses Wesleyan and broadly Christian voices that explore the theological, philosophical, biblical, ethical, and practical implications of emerging technologies, their impact upon different aspects of human life, and the possibilities that are opening up toward a posthuman future.